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ChemicalBook CAS DataBase List N-Formyl-4-(methylamino)benzoic acid
51865-84-0

N-Formyl-4-(methylamino)benzoic acid synthesis

2synthesis methods
-

Yield:51865-84-0 97%

Reaction Conditions:

in formic acid;water;

Steps:

1 EXAMPLE 1

EXAMPLE 1 10.0 g. (0.066 mole) of p-(N-methyl)-aminobenzoic acid was boiled under reflux free of water in 100 ml of formic acid for 3 hrs., and then evaporated to dryness. The reaction product, p-(N-methyl-N-formyl)-aminobenzoic acid, can be isolated in pure form (white crystals having a melting point of 218° C.) by suspension in water or preferably by reprecipitation in water or preferably by reprecipitation by means of NaOH/HCl at 97 percent yield.

References:

US4211883,1980,A

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