ChemicalBook CAS DataBase List METHYLENECYCLOPENTANE

METHYLENECYCLOPENTANE synthesis

15synthesis methods

Product Name:METHYLENECYCLOPENTANE
CAS Number:1528-30-9
Molecular formula:C6H10
Molecular Weight:82.14

75-09-2 Synthesis

75-09-2
1215 suppliers
$10.00/25 mL

32916-51-1
89 suppliers
$54.70/100ml

1528-30-9
70 suppliers
$49.00/1mL

1640-89-7
40 suppliers
$45.00/10mg

Yield: 79.3% ， 11.3%

Reaction Conditions:

with C₃₁H₃₇ClN₃NiO₂^(1-)*Li⁽¹⁺⁾ in tetrahydrofuran at 25; for 0.333333 h;Inert atmosphere;Overall yield = 90.4 %;

Steps:

2.4 Cross coupling of CH₂Cl₂ with butylmagnesium chloride
General procedure: Cross-coupling reactions of Grignard reagents with CH₂Cl₂ were performed according to the following general method. Catalyst 2 (1.0 mg, 1.74 μmol) in 1.0 mL THF was added using a gas-tight syringe to a 5 mL round bottom flask purged with N₂. To this solution, 2 M n-butylmagnesium chloride in THF (0.42 mL, 0.84 mmol) was added. CH₂Cl₂ (27 μL, 0.42 mmol) in 2 mL THF was added to the reaction mixture. Samples were collected for analysis after 20 min. At the end of the reaction, excess Grignard reagent was destroyed using methanol and the reaction products were analyzed by GC-MS using an internal standard to quantify product formation.

References:

Gartia, Yashraj;Nasini, Udaya Bhasker;Ghosh, Anindya;Biswas, Abhijit;Stadler, Matthew [Journal of Molecular Catalysis A: Chemical,2012,vol. 363-364,p. 322 - 327,6]