ChemicalBook CAS DataBase List METHYL 4'-METHOXYBIPHENYL-4-CARBOXYLATE

METHYL 4'-METHOXYBIPHENYL-4-CARBOXYLATE synthesis

13synthesis methods

Product Name:METHYL 4'-METHOXYBIPHENYL-4-CARBOXYLATE
CAS Number:729-17-9
Molecular formula:C15H14O3
Molecular Weight:242.27

104-92-7 Synthesis

104-92-7
427 suppliers
$10.00/10g

99768-12-4 Synthesis

99768-12-4
368 suppliers
$10.00/1g

729-17-9
32 suppliers
$55.00/100mg

Yield:729-17-9 98%

Reaction Conditions:

with potassium carbonate in ethanol;water at 50; for 2.5 h;Inert atmosphere;Schlenk technique;Suzuki-Miyaura Coupling;

Steps:

2.4. General procedure for Suzuki-Miyaura coupling reaction

General procedure: A Schlenk tube was charged with a suspension of aryl halide (1.0mmol), arylboronic acid (1.2 mmol), potassium carbonate (276 mg,2.0 mmol) and Pd/HCCP-DABP (20 mg, 0.3 mol%) in EtOH-H2O (3 mL,v:v=1:1), evacuated, and backfilled with nitrogen. The resulting reaction mixture was stirred at 50 °C for 2.5 h. After completion of the reaction,the mixture was cooled and extracted with CH2Cl2. The combined organic phase was dried, evaporated and purified by column chromatographyon silica gel to give the coupling product. The aqueous phasewas filtered and the solid was washed with CH2Cl2 and reused in further reactions as the recovered catalyst.

References:

Wang, Yiming;Lu, Cuifen;Yang, Guichun;Chen, Zuxing;Nie, Junqi [Reactive and functional polymers,2017,vol. 110,p. 38 - 46]

619-42-1 Synthesis