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ChemicalBook CAS DataBase List METHYL 10,12-TRICOSADIYNOATE
145609-79-6

METHYL 10,12-TRICOSADIYNOATE synthesis

2synthesis methods
66990-30-5 Synthesis
10,12-TRICOSADIYNOIC ACID

66990-30-5
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$14.00/100mg

METHYL 10,12-TRICOSADIYNOATE

145609-79-6
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Yield:145609-79-6 2.68 g (74%)

Reaction Conditions:

with sulfuric acid in methanol;

Steps:

13.a a

a Methyl 10,12-tricosadiynoate 10,12- Tricosadiynoic acid (3.0 g, 0.0084 mol), methanol (15 ml) and concentrated sulfuric acid (0.8 ml) were heated to reflux and stirred for 1 hour. The cooled mixture was taken up in either (40 ml) and washed with 10% NaHCO3 (20 ml) and water (20 ml), and the organic phase was dried (MgSO4). Evaporation of the solvent gave 2.68 g (74%) of the title compound. 1 H NMR (60 MHz, CDCl3): δ 0.98 (m, 3H, CH3 CH2), 1.28 (m, 28H, CH2), 2.25 (m, 6H, CH2), 3.70 (s, 3H, CH2 O).

References:

US6106806,2000,A

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