Laurocapram synthesis
- Product Name:Laurocapram
- CAS Number:59227-89-3
- Molecular formula:C18H35NO
- Molecular Weight:281.48
105-60-2
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143-15-7
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59227-89-3
454 suppliers
$6.00/25g
Yield:59227-89-3 99.6%
Reaction Conditions:
with sodium hydroxide in water;toluene;
Steps:
1 EXAMPLE 1
EXAMPLE 1 A 1l reactor is charged with 34 g (0.3 mole) of azacycloheptane-2-one, 112 g (0.45 mole) of dodecyl bromide, 300 g of toluene, 3.4 g (3.3 mole % based on the azacycloheptane-2-one) of crystalline tetrabutylammonium hydrogensulfate (TBAHS) and 90 g (2.25 moles) of flaky sodium hydroxide. This heterogeneous mixture was stirred at 50° C. for 10 hours. After the mixture was cooled to 40° C., 135 g of water was added to the mixture, followed by stirring at 40° C. for 30 minutes. The oil layer was separated and the oil layer thus obtained was subjected to distillation, giving 84.0 g of 1-dodecylazacycloheptane-2-one having a boiling point of 195° to 200° C./3 mmHg (yield of 99.6% based on the azacycloheptane-2-one), and also 0.8 g of dodecyl ether (yield of 1.0% based on the dodecyl bromide).
References:
US4812566,1989,A
143-15-7
441 suppliers
$5.00/25g
59227-89-3
454 suppliers
$6.00/25g
112-52-7
278 suppliers
$7.00/25g
59227-89-3
454 suppliers
$6.00/25g
105-60-2
530 suppliers
$5.00/25g
1634-04-4
665 suppliers
$14.00/100g
143-15-7
441 suppliers
$5.00/25g
59227-89-3
454 suppliers
$6.00/25g
112-53-8
441 suppliers
$10.00/5g
59227-89-3
454 suppliers
$6.00/25g