天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List L-Glutamic acid α-tert·butyl ester
45120-30-7

L-Glutamic acid α-tert·butyl ester synthesis

5synthesis methods
-

Yield:45120-30-7 11.55 g (77%)

Reaction Conditions:

palladium-carbon in methanol;

Steps:

29.A Step A

Step A Preparation of (S)-2-aminopentanedioic acid 1-tert.-butyl ester To a solution of 25.0 g (74.1 mmol) (S)-2-(benzyloxycarbonylamino)pentanedioic acid 1-tert.-butyl ester (prepared according to Liebigs Ann. Chem. 1961, 646, 127) in 500 ml dry methanol were added 2.5 g 10% Pd/C, and the mixture was stirred over night at room temperature under an atmosphere of hydrogen. The catalyst was removed by filtration through celite and the filtrate was concentrated under reduced pressure. The remaining solid title compound was purified by stirring with a small amount of ethanol, filtered with suction, and dried in vacuo. Another crop (1.7 g) was obtained after concentration of the mother liquid and stirring of the residue with ethyl acetate. total yield: 11.55 g (77%), white powder, m.p. 114-116° C.

References:

US6291469,2001,B1

L-Glutamic acid α-tert·butyl ester Related Search: