Hexylamine synthesis
- Product Name:Hexylamine
- CAS Number:111-26-2
- Molecular formula:C6H15N
- Molecular Weight:101.19
646-14-0
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$70.09/1g
111-26-2
192 suppliers
$10.00/5g
Yield:111-26-2 100%
Reaction Conditions:
with trichlorosilane;N-ethyl-N,N-diisopropylamine in acetonitrile at 15; for 18 h;
Steps:
1 General procedure for the reduction of aliphatic nitro derivatives.
DIPEA (5 mmol/eq) was added to a solution of 1-nitro-n-hexane (1 mmol/eq) in acetonitrile at 15°C, maintained under stirring. Freshly distilled trichlorosilane (3.5 mmol/eq) was then added dropwise with a syringe. After leaving under stirring for 18 hours at 15°C, the reaction was quenched by adding 10% NaOH, and the mixture was extracted with AcOEt. The combined organic phases were dried on Na2SO4, filtered and concentrated under vacuum to give the corresponding amine in a quantitative yield.
References:
WO2014/37444,2014,A1 Location in patent:Page/Page column 6
66-25-1
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$16.80/100G
111-26-2
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$10.00/5g
628-73-9
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$15.00/1g
111-26-2
192 suppliers
$10.00/5g
628-02-4
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$28.00/1g
111-26-2
192 suppliers
$10.00/5g