ETHYL (S)-3,4-EPOXYBUTANOATE synthesis
- Product Name:ETHYL (S)-3,4-EPOXYBUTANOATE
- CAS Number:112083-63-3
- Molecular formula:C6H10O3
- Molecular Weight:130.14
32223-97-5
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112083-63-3
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Yield:> 99 % ee
Reaction Conditions:
with water;[(1-SS)-(Dibenzoyl-DTA)] at 5 - 20;Product distribution / selectivity;Resolution of racemate;
Steps:
25
0.5 mole of racemic 1,2-epoxy compounds were added with 0.4 mole % of the catalyst prepared in Preparation Example 1 [(1-RR)-(Dibenzoyl-LTA) ] (or Preparation Example 2 [ (1-SS) - (Dibenzoyl- DTA)]) and cooled down to 5 °G Then 5.4 g of water was slowly added here and stirred at 20 °C After fractional distillation under reduced pressure, the target compounds were obtained with more than 99%ee optical purity
References:
WO2008/153280,2008,A1 Location in patent:Page/Page column 39; 40
32223-97-5
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112083-63-3
58 suppliers
$177.00/500mg
112635-76-4
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112100-39-7
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112083-63-3
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![Butanoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-iodo-, ethyl ester, (3S)-](/CAS/20210305/GIF/130158-22-4.gif)
130158-22-4
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112083-63-3
58 suppliers
$177.00/500mg