天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

105224-04-2

Ethanone, 1-(3-methyl-1H-pyrazol-4-yl)- (9CI) synthesis

9synthesis methods
-

Yield:105224-04-2 88%

Reaction Conditions:

with hydrazine hydrate in ethanol;Reflux;

Steps:



General procedure: To a stirred (m)ethanolic solution (only 5b in methanol) of hydrazine hydrate (17.2 mmol) was added enol ether 3a-d (17.2 mmol) dropwise at rt. The reaction mixture was heated under reflux for 1-1.5 h. After cooling the crude product was filtered and recrystallized from the appropriate solvent or purified by column chromatography.

References:

Tarabova, Denisa;Soralova, Stanislava;Breza, Martin;Fronc, Marek;Holzer, Wolfgang;Milata, Viktor [Beilstein Journal of Organic Chemistry,2014,vol. 10,p. 752 - 760] Location in patent:supporting information