Doqualast synthesis
1synthesis methods
- Product Name:Doqualast
- CAS Number:64019-03-0
- Molecular formula:C13H8N2O3
- Molecular Weight:240.21
![11H-Pyrido[2,1-b]quinazolin-11-one, 2-bromo-](/CAS/20210111/GIF/71937-21-8.gif)
Yield:64019-03-0 48%
Reaction Conditions:
with calcium hydroxide;nickel carbonyl;water in N,N-dimethyl-formamide at 110 - 115; under 2068.6 Torr;
References:
Tilley;LeMahieu;Carson;Kierstead;Baruth;Yaremko [Journal of Medicinal Chemistry,1980,vol. 23,# 1,p. 92 - 95]