Cypermethrin synthesis
- Product Name:Cypermethrin
- CAS Number:52315-07-8
- Molecular formula:C22H19Cl2NO3
- Molecular Weight:416.3
52314-67-7
106 suppliers
$66.00/50mg
39515-51-0
411 suppliers
$10.00/5g
52315-07-8
335 suppliers
$31.00/50mg
Yield:52315-07-8 95.5%
Reaction Conditions:
in tetrahydrofuran;dichloromethane;water;
Steps:
1.2 A.
(2) To a stirred solution of sodium cyanide (2.40 g, 0.049 mole) in a 1:1 by volume mixture of water and tetrahydrofuran (50 ml) at 15° was added dropwise over 30 minutes a mixture of 3-phenoxybenzaldehyde (7.00 g, 0.035 mole) and 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarbonyl chloride (10.00 g, 0.042 mole). Stirring was continued at 15° for an additional 2 hours, after which the reaction mixture was extracted thrice with methylene chloride (40 ml each). The combined organic layers were washed once with aqueous 2 N NaOH (50 ml), four times with waer (50 ml portions) to a final wash pH of about 6, then dried over MgSO4 and concentrated to give α-cyano-3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate (13.9 g, 95.5% yield).
References:
US4299776,1981,A
773837-37-9
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52314-67-7
106 suppliers
$66.00/50mg
39515-51-0
411 suppliers
$10.00/5g
52315-07-8
335 suppliers
$31.00/50mg
39515-51-0
411 suppliers
$10.00/5g
52315-07-8
335 suppliers
$31.00/50mg
123-91-1
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52314-67-7
106 suppliers
$66.00/50mg
39515-51-0
411 suppliers
$10.00/5g
52315-07-8
335 suppliers
$31.00/50mg
280-57-9
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52314-67-7
106 suppliers
$66.00/50mg
39515-51-0
411 suppliers
$10.00/5g
52315-07-8
335 suppliers
$31.00/50mg