ChemicalBook CAS DataBase List CYCLOOCTANONE

CYCLOOCTANONE synthesis

10synthesis methods

Product Name:CYCLOOCTANONE
CAS Number:502-49-8
Molecular formula:C8H14O
Molecular Weight:126.2

292-64-8
89 suppliers
$23.00/25mL

502-49-8
279 suppliers
$8.00/5g

696-71-9
78 suppliers
$45.60/25 mL

Yield:696-71-9 13% ，502-49-8 77%

Reaction Conditions:

with [Fe₄^III(μ-O)₂(μ-acetate)₆(2,2'-bipyridine)₂(H₂O)₂](NO₃^-)(OH^-);dihydrogen peroxide;acetic acid in water;acetonitrile at 32; for 3 h;Catalytic behavior;Overall yield = 89 %Spectr.;

Steps:

2.4. C-H activation analysis by the oxido-acetato-bridged tetraironcomplex (1)
General procedure: Conversion of cyclooctane: Cyclooctane (228 mg, 268 ml,2 mmol) was added to a solution of 1 (0.04 mmol) in MeCN:aceticacid (1.5:0.5 ml) in over all catalyst 1: substrate: oxidant0.04:200:500). After the addition of H2O2 (33% in H2O; 454 mL,5.0 mmol), the reaction mixture was heated at 32 °C for 3 h. Themixturewas then allowed to cool to room temperature. The organicphase was extracted with Et2O (3 x 1 ml), washed with brine anddried (MgSO4). After filtration, the solvents of the filtrate wereevaporated (rotary evaporator). The remaining mixture was separatedby column chromatography (silica gel; diethyl ether:pentane 1:20 as eluent) and the product was analyzed by GC-MSusing 1,2-dichlorobenzene as an internal standard.

References:

Dey, Dhananjay;Patra, Moumita;Al-Hunaiti, Afnan;Yadav, Hare Ram;Al-mherat, Afrah;Arar, Sharif;Maji, Milan;Choudhury, Angshuman Roy;Biswas, Bhaskar [Journal of Molecular Structure,2019,vol. 1180,p. 220 - 226]

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696-71-9
78 suppliers
$45.60/25 mL

502-49-8
279 suppliers
$8.00/5g

References

292-64-8
89 suppliers
$23.00/25mL

201230-82-2 Synthesis