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83490-13-5

CHEMBRDG-BB 6423830 synthesis

4synthesis methods
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Yield:83490-13-5 75%

Reaction Conditions:

Stage #1: 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dionewith pyridine;palladium diacetate;copper(II) acetate monohydrate in 1,4-dioxane at 20; for 0.166667 h;Inert atmosphere;
Stage #2: furfural in 1,4-dioxane at 120; for 20 h;Inert atmosphere;

References:

Xi, Peihua;Yang, Fan;Qin, Song;Zhao, Dongbing;Lan, Jingbo;Gao, Ge;Hu, Changwei;You, Jingsong [Journal of the American Chemical Society,2010,vol. 132,# 6,p. 1822 - 1824] Location in patent:supporting information; experimental part

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