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ChemicalBook CAS DataBase List C-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-methylamine
50675-25-7

C-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-methylamine synthesis

2synthesis methods
60549-63-5 Synthesis
2,2-dimethyltetrahydro-2H-pyran-4-carbonitrile(SALTDATA: FREE)

60549-63-5
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Yield:50675-25-7 45.7%

Steps:

67.1 Step 1:

Step 1:
Synthesis of (2,2-dimethyltetrahydro-2H-pyran-4-yl)methanamine
2,2-Dimethyltetrahydro-2H-pyran-4-carbonitrile (1.000 g, 7.184 mmol) as a starting material was used in a similar manner to Step 1-2 of Example 34 to obtain (2,2-dimethyltetrahydro-2H-pyran-4-yl)methanamine (0.470 g, 45.7%, yellow oil): LRMS (ES) m/z 144.07 [M+H]+, calculated MW 143.23.

References:

US2022/274939,2022,A1

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