BUTTPARK 120\07-77 synthesis
- Product Name:BUTTPARK 120\07-77
- CAS Number:189940-04-3
- Molecular formula:C9H6F3NO2
- Molecular Weight:217.14
![Acetamide, 2-chloro-N-[2-hydroxy-5-(trifluoromethyl)phenyl]-](/CAS/20210305/GIF/888731-86-0.gif)
888731-86-0
0 suppliers
inquiry
189940-04-3
17 suppliers
$65.00/50mg
Yield:-
Reaction Conditions:
with potassium carbonate in water;N,N-dimethyl-formamide;
Steps:
R.85.3 Production of 6-trifluoromethyl-4H-benzo[1,4]oxazin-3-one
Step 3 Production of 6-trifluoromethyl-4H-benzo[1,4]oxazin-3-one 2-Chloro-N-(2-hydroxy-5-trifluoromethylphenyl)acetamide (1.4244 g) was dissolved in N,N-dimethylformamide (14 mL), and potassium carbonate (1.0072 g) was added at room temperature. After stirring at room temperature for 2 hrs, water (20 mL) was added, and the mixture was extracted with ethyl acetate. The obtained ethyl acetate layer was washed with water and saturated brine, and dried over anhydrous sodium sulfate. The solvent was evaporated to give the title compound (1.2084 g) as a pale-gray solid.
References:
US2008/305169,2008,A1
400-99-7
177 suppliers
$19.00/5g
189940-04-3
17 suppliers
$65.00/50mg
454-81-9
123 suppliers
$22.00/250mg
189940-04-3
17 suppliers
$65.00/50mg