Yield:38002-95-8 86%

Reaction Conditions:

with C₆H₄MoNO₇^(1-)*C₁₉H₄₂N⁽¹⁺⁾;oxygen in water at 100; for 20 h;Green chemistry;chemoselective reaction;

Steps:

2.3. General procedure for the catalytic oxidation of alcohols toaldehydes

General procedure: A mixture of alcohol (0.75 mmol), and catalyst Mo1 (13 mg,3.0 mol%) taken in 0.5 mL of water was stirred at 100 ° C under oxygenatmosphere (O2 bladder) and the stirring was continued for16-24 h as per requirement. The progress of reaction was monitoredby TLC. After completion of the reaction, ethyl acetate was added to the mixture. The aqueous phase was extracted with ethyl acetate 2-3 times. Then the combined organic extracts were driedover anhydrous sodium sulfate and the solvent was removed under reduced pressure. The crude product so obtained was purified by column chromatography using hexane-ethyl acetate as eluent. While the known products were characterized by spectroscopic techniques and compared with reported data and the new products 22b and 36b were characterized completely. The characterization detail is provided in supporting information section.

References:

Thiruvengetam, Prabaharan;Chakravarthy, Rajan Deepan;Chand, Dillip Kumar [Journal of Catalysis,2019,vol. 376,p. 123 - 133]