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25375-38-6

Androst-5-en-17-one, 3-hydroxy- synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / 5 h / 20 - 25 °C
2: toluene-4-sulfonic acid; trimethyl orthoformate / 6 h / 20 - 25 °C
3: sodium tetrahydroborate; ethanol / ethanol / 0 - 25 °C
4: acetic acid / acetone / 20 - 25 °C

References:

CN106928301,2017,A