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ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla synthesis

1synthesis methods

Product Name:ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla
CAS Number:99696-21-6
Molecular formula:C15H12ClF2NO3
Molecular Weight:327.71

Yield:-

Reaction Conditions:

with sodium hydride in 1,4-dioxane; for 2 h;Ambient temperature;

References:

Kimura;Atarashi;Kawakami;Sato;Hayakawa [Journal of Medicinal Chemistry,1994,vol. 37,# 20,p. 3344 - 3352]