4-(4-MORPHOLINOMETHYL)-PHENYLBORONIC ACID PINACOL ESTER HYDROCHLORIDE synthesis
- Product Name:4-(4-MORPHOLINOMETHYL)-PHENYLBORONIC ACID PINACOL ESTER HYDROCHLORIDE
- CAS Number:944591-57-5
- Molecular formula:C17H27BClNO3
- Molecular Weight:339.67
944591-57-5
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1142943-96-1
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1142938-50-8
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Yield:1142938-50-8 100%
Reaction Conditions:
with (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride;potassium carbonate in 1,4-dioxane;water at 140; for 0.5 h;Microwave irradiation;
References:
Menet, Christel J.;Fletcher, Stephen R.;Van Lommen, Guy;Geney, Raphael;Blanc, Javier;Smits, Koen;Jouannigot, Nolwenn;Deprez, Pierre;Van Der Aar, Ellen M.;Clement-Lacroix, Philippe;Lepescheux, Liên;Galien, René;Vayssiere, Béatrice;Nelles, Luc;Christophe, Thierry;Brys, Reginald;Uhring, Muriel;Ciesielski, Fabrice;Van Rompaey, Luc [Journal of Medicinal Chemistry,2014,vol. 57,# 22,p. 9323 - 9342]