3-(4-Bromophenyl)-1-(4-methoxyphenyl)-2-propen-1-one synthesis
4synthesis methods
- Product Name:3-(4-Bromophenyl)-1-(4-methoxyphenyl)-2-propen-1-one
- CAS Number:92873-00-2
- Molecular formula:C16H13BrO2
- Molecular Weight:317.1772
Yield:92873-00-2 93%
Reaction Conditions:
Stage #1: 1-(4-methoxylphenyl)-2-propen-1-olwith oxygen;palladium diacetate in N,N-dimethyl-formamide at 90; under 760.051 Torr; for 4 h;Green chemistry;
Stage #2: 4-Bromophenylboronic acidwith 2.9-dimethyl-1,10-phenanthroline in N,N-dimethyl-formamide at 90; for 18 h;Green chemistry;chemoselective reaction;Heck Reaction;
References:
Vellakkaran, Mari;Andappan, Murugaiah M. S.;Nagaiah, Kommu [RSC Advances,2014,vol. 4,# 85,p. 45490 - 45494]