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ChemicalBook CAS DataBase List A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID
881016-89-3

A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID synthesis

4synthesis methods
tert-butyl 4-(1-bromo-2-methoxy-2-oxoethyl)piperidine-1-carboxylate

881016-88-2
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A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID

881016-89-3
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Yield:881016-89-3 66%

Reaction Conditions:

with lithium hydroxide in tetrahydrofuran;methanol at 20;

References:

Xia, Mingde;Hou, Cuifen;DeMong, Duane E.;Pollack, Scott R.;Pan, Meng;Brackley, James A.;Jain, Nareshkumar;Gerchak, Chrissy;Singer, Monica;Malaviya, Ravi;Matheis, Michele;Olini, Gil;Cavender, Druie;Wachter, Michael [Journal of Medicinal Chemistry,2007,vol. 50,# 23,p. 5561 - 5563]

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