ChemicalBook CAS DataBase List N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide synthesis

3synthesis methods

Product Name:N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
CAS Number:76820-34-3
Molecular formula:C14H19N3O8
Molecular Weight:357.32

13552-31-3 Synthesis

13552-31-3
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13290-96-5 Synthesis

13290-96-5
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N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide

76820-34-3
86 suppliers
$160.00/500mg

Yield:76820-34-3 85%

Reaction Conditions:

in methanol;

Steps:

5.f f)

f) 5-Nitro-N,N'-bis-(2,3-dihydroxypropyl)isophthalamide To a solution of 5-nitroisophthalic acid dimethyl ester (23.92 g, 0.1 moles) in methanol (100 mL), 3-amino-1,2-propanediol (16.52 g, 0.22 moles) was added with stirring and heated at solvent reflux for four hours. The solution was evaporated to dryness under reduced pressure. The crude was crystallized inmethanol/ethyl ether, filtered off, and dried in vacuo to obtain 5-nitro-N,N'-bis-(2,3-dihydroxypropyl)isophthalamide (30.3 g, 85%).

References:

EP1186305,2002,A1

13552-31-3 Synthesis

13552-31-3
1 suppliers
inquiry

13290-96-5 Synthesis

13290-96-5
389 suppliers
$8.00/25g