Benzene, 1-(1-Methylethenyl)-2,4-bis(phenylMethoxy)- synthesis

6synthesis methods

Product Name:Benzene, 1-(1-Methylethenyl)-2,4-bis(phenylMethoxy)-
CAS Number:747414-16-0
Molecular formula:C23H22O2
Molecular Weight:330.42

22877-01-6
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$21.00/250mg

1779-49-3
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$5.00/10g

Benzene, 1-(1-Methylethenyl)-2,4-bis(phenylMethoxy)-

747414-16-0
21 suppliers
$117.00/50mg

Yield:747414-16-0 80%

Reaction Conditions:

Stage #1: Methyltriphenylphosphonium bromidewith n-butyllithium in tetrahydrofuran;hexane at 0; for 0.5 h;
Stage #2: 2,4-bis(benzyloxy)acetophenone in tetrahydrofuran;hexane at 20; for 18 h;Further stages.;Wittig reaction;

References:

Brough, Paul A.;Aherne, Wynne;Barril, Xavier;Borgognoni, Jenifer;Boxall, Kathy;Cansfield, Julie E.;Cheung, Kwai-Ming J.;Collins, Ian;Davies, Nicholas G. M.;Drysdale, Martin J.;Dymock, Brian;Eccles, Suzanne A.;Finch, Harry;Fink, Alexandra;Hayes, Angela;Howes, Robert;Hubbard, Roderick E.;James, Karen;Jordan, Allan M.;Lockie, Andrea;Martins, Vanessa;Massey, Andrew;Matthews, Thomas P.;McDonald, Edward;Northfield, Christopher J.;Pearl, Laurence H.;Prodromou, Chrisostomos;Ray, Stuart;Raynaud, Florence I.;Roughley, Stephen D.;Sharp, Swee Y.;Surgenor, Allan;Walmsley, D. Lee;Webb, Paul;Wood, Mike;Workman, Paul;Wright, Lisa [Journal of Medicinal Chemistry,2008,vol. 51,# 2,p. 196 - 218]

22877-01-6
75 suppliers
$21.00/250mg