7-METHOXY-8-METHYL-CHROMEN-2-ONE synthesis
- Product Name:7-METHOXY-8-METHYL-CHROMEN-2-ONE
- CAS Number:14002-94-9
- Molecular formula:C11H10O3
- Molecular Weight:190.2
Yield:14002-94-9 36%
Reaction Conditions:
Stage #1: 7-hydroxy-8-methyl-2H-chromen-2-onewith sodium hydride in N,N-dimethyl-formamide at 0; for 0.333333 h;
Stage #2: methyl iodidewith sodium hydride in N,N-dimethyl-formamide at 0 - 20; for 5 h;
References:
Leonetti, Francesco;Favia, Angelo;Rao, Angela;Aliano, Rosaria;Paluszcak, Anja;Hartmann, Rolf W.;Carotti, Angelo [Journal of Medicinal Chemistry,2004,vol. 47,# 27,p. 6792 - 6803]
15568-85-1
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14002-94-9
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