天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

3835-21-0

6-methoxy-2,3-dihydro-1H-quinolin-4-one synthesis

9synthesis methods
-

Yield:3835-21-0 90.9%

Reaction Conditions:

with hydrogenchloride;acetic acid in water at 80; for 8 h;

Steps:

1.4 Preparation of 6-methoxy-2,3-dihydro-4(1H)-quinolinone

N-p-toluenesulfonyl-6-methoxy-2,3-dihydro-quinolinone 24.8g (74.8mmol) was added three 250ml bottle, then concentrated hydrochloric acid was added with good: acetic acid: water = 2: 2:1 (V / V / V) mixture of 125ml, 80 ° C reaction 8h, reaction completion, -0.06 ~ -0.01Mpa reaction mixture was evaporated to 1/4 of the original solution, potassium hydroxide solution was adjusted pH with saturated hydrogen 10, filtration, and dried to give a yellow solid 12.1g, yield: 90.9%.

References:

CN103772276,2016,B Location in patent:Paragraph 0049; 0060-0061