6,7-DICHLORO-QUINOXALIN-2-YLAMINE synthesis
- Product Name:6,7-DICHLORO-QUINOXALIN-2-YLAMINE
- CAS Number:76002-68-1
- Molecular formula:C8H5Cl2N3
- Molecular Weight:214.05
5348-42-5
228 suppliers
$6.00/1g
58590-56-0
2 suppliers
inquiry
2244-11-3
186 suppliers
$20.00/5g
76002-68-1
9 suppliers
inquiry
Yield:-
Reaction Conditions:
with boric acid in sulfuric acid;acetic acid;
Steps:
2.A STEP A:
STEP A: 2-amino-6,7-dichloro-quinoxaline A solution of 10 g of 4,5-dichloro-o-phenylenediamine, 9 g of alloxan hydrate, 1.5 g of boric acid and 250 ml of glacial acetic acid was stirred overnight at room temperature to obtain a brown-black solution which was filtered. The yellow-buff crystalline solid was well washed with water to obtain 15.9 g of 7,8-dichloro-alloxazine melting at >370° C. A solution of 2 g of 7,8-dichloro-alloxazine in 10 ml of concentrated sulfuric acid was slowly heated to 240° C. and held there for 10 minutes. The mixture was cooled and poured onto ice and the mixture was made alkaline with sodium hydroxide addition. The mixture was extracted several times with ether to obtain 0.73 g of 2-amino-6,7-dichloro-quinoxaline as an orange crystalline solid melting at 220° C. Analysis: C8 H5 N3 Cl2: Calculated: %C 44.89; %H 2.35; %N 19.63. Found: %C 44.96; %H 2.55; %N 19.23.
References:
US4254123,1981,A
58590-56-0
2 suppliers
inquiry
76002-68-1
9 suppliers
inquiry
5348-42-5
228 suppliers
$6.00/1g
76002-68-1
9 suppliers
inquiry