5-AMINO-1-(3,4-DICHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE synthesis
- Product Name:5-AMINO-1-(3,4-DICHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
- CAS Number:58791-78-9
- Molecular formula:C10H6Cl2N4
- Molecular Weight:253.09
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Yield:-
Reaction Conditions:
Stage #1: 3,4-dichlorophenylhydrazine hydrochloridewith anhydrous Sodium acetate in ethanol; for 0.5 h;Reflux;
Stage #2: Ethoxymethylenemalononitrile in ethanol; for 1 h;Reflux;
References:
Dos Santos, Mauricio S.;Oliveira, Mariana L.V.;Bernardino, Alice M.R.;De Leo, Rosa M.;Amaral, Veronica F.;De Carvalho, Flavia T.;Leon, Leonor L.;Canto-Cavalheiro, Marilene M. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 24,p. 7451 - 7454] Location in patent:scheme or table
