3-Chloro-benzo[d]isothiazole 1,1-dioxide synthesis
- Product Name:3-Chloro-benzo[d]isothiazole 1,1-dioxide
- CAS Number:567-19-1
- Molecular formula:C7H4ClNO2S
- Molecular Weight:201.63
81-07-2
446 suppliers
$13.98/25G
567-19-1
58 suppliers
$65.00/50mg
Yield: 99%
Reaction Conditions:
with thionyl chloride;N,N-dimethyl-formamide in 1,4-dioxane for 24 h;Reflux;
Steps:
1.A Step A: 3-chloro-1,2-benzothiazole-1,1-dioxide
A mixture of saccharin (70.00 g; 382.13 mmol; 1.00 eq.), thionyl chloride (41.58 ml; 573.19 mmol; 1.50 eq.) and a catalytic amount of DMF (2.10 ml) in 1,4-dioxane (350 ml) was heated for 24h under reflux. The reaction mixture was concentrated, co-evaporated 4 times with toluene (200 ml) and dried to give 3-chloro-1,2-benzothiazole-1,1-dioxide (77.00 g; 99 %), used without further purification
References:
Eng Bang Tiba;Ba Seu-ma-tin;Kon Tal-sil-bi-e;Ju Ni-en-jang---ru-i-seu;Ma Sa-reu-di-e-reu-keu-ri-seu-tin;Mon Tal-be-ti-keu-ri-seu-chan;Su Deu-an-ne KR2019/137803, 2019, A Location in patent:Paragraph 0384-0386
![Benzo[d]isothiazole 1,1-dioxide](/CAS/20180629/GIF/5669-05-6.gif)
5669-05-6
6 suppliers
inquiry
567-19-1
58 suppliers
$65.00/50mg
7719-09-7
406 suppliers
$15.00/10g
81-07-2
446 suppliers
$13.98/25G
567-19-1
58 suppliers
$65.00/50mg