5-(2-ADAMANTYLIDENE)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE synthesis
- Product Name:5-(2-ADAMANTYLIDENE)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
- CAS Number:51757-47-2
- Molecular formula:C16H20O4
- Molecular Weight:276.33
2033-24-1
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700-58-3
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51757-47-2
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$179.00/5g
Yield:51757-47-2 88%
Reaction Conditions:
with pyridine;piperidine for 120 h;Knoevenagel Condensation;
Steps:
Compound IA. 5-(2-Adamantylidene)-2,2-dimethyl-l,3-dioxane-4,6-dione[00118] This material is commercially available from the Aldrich Company. It can also be synthesized using the following procedure: A solution of 2-adamantanone (1.5 g, 10 mmol), Meldrum's acid (1.73 g, 12 mmol), and a catalytic amount of piperidine (5 drops) in anhydrous pyridine (10 mL) was stirred under argon for 5 days. After this time, the solution was poured into ice water (30 mL), and the resulting mixture
References:
WO2008/24892,2008,A2 Location in patent:Page/Page column 69-70