5-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE synthesis
- Product Name:5-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
- CAS Number:98700-50-6
- Molecular formula:C11H10N2O
- Molecular Weight:186.21
153863-35-5
50 suppliers
$29.00/1g
98700-50-6
39 suppliers
$87.00/250mg
Yield:98700-50-6 95%
Reaction Conditions:
with 4-methylmorpholine N-oxide;tetrapropylammonium perruthennate in dichloromethane; for 0.666667 h;Molecular sieve;
Steps:
5
Tetrapropylammonium perruthenate (76 mg) was added to a mixture of (5-methyl-1- phenyl-1 H-pyrazol-4~yl)methanol (816 mg, 4.3 mmol), 4-methylmorpholine N-oxide (754 mg, 6.45 mmol) and molecular sieves (4 A) in dry dichloromethane (12.6 ml). The reaction was stirred for 40 minutes then filtered through a silica plug washing with dichloromethane. Concentration yielded 5-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde as a pale yellow solid (763 mg, 95 %).LCMS (A) Rt = 2.39 minutes; m/z [M+H]+ = 187
References:
WO2006/67462,2006,A1 Location in patent:Page/Page column 47
59-88-1
360 suppliers
$15.00/10g
98700-50-6
39 suppliers
$87.00/250mg
89193-16-8
68 suppliers
$21.21/250mgs:
98700-50-6
39 suppliers
$87.00/250mg
100-63-0
362 suppliers
$10.00/1g
98700-50-6
39 suppliers
$87.00/250mg
7189-01-7
9 suppliers
inquiry
98700-50-6
39 suppliers
$87.00/250mg