5-Hydroxy-1-tetralone synthesis
- Product Name:5-Hydroxy-1-tetralone
- CAS Number:28315-93-7
- Molecular formula:C10H10O2
- Molecular Weight:162.19
83-56-7
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$9.00/25g
28315-93-7
292 suppliers
$7.00/250mg
Yield:28315-93-7 83.3%
Reaction Conditions:
with palladium on activated charcoal;ammonium formate in water;butan-1-ol at 120; for 3 h;Further stages;Temperature;Solvent;Reagent/catalyst;
Steps:
2 Example 2
Mixing 32 g of 1,5-dihydroxynaphthalene, 8 g of water, 152 g of n-butanol, 3.2 g of palladium on carbon and 12.6 g of ammonium formate,The reaction was heated to 120 ° C under normal pressure for 3 h, and 12 g of sodium hydroxide was added to the obtained system.Stir and heat filtration, and adjust the pH of the obtained filtrate to 3 with industrial hydrochloric acid having a mass concentration of 31%.After the solid was precipitated, it was suction filtered, and the obtained cake was recrystallized from methanol and water (volume ratio of methanol to water: 4:1).Drying in vacuo gave 27.0 g of 5-hydroxy-1-tetralone.The liquid phase purity is greater than 99% and the yield is 83.3%.
References:
Hangzhou Normal University;Hangzhou Lupu Biological Technology Co., Ltd.;Xu Weiming;Zhang Pengfei;Feng Dongxiang;Tao Lianzhi CN109160882, 2019, A Location in patent:Paragraph 0041-0043-0044; 0048-0049; 0051-0052; 0054-0055
33892-75-0
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$8.00/1g
28315-93-7
292 suppliers
$7.00/250mg
40771-26-4
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$85.00/100mg
28315-93-7
292 suppliers
$7.00/250mg
91028-13-6
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28315-93-7
292 suppliers
$7.00/250mg