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912454-38-7

5-bromo-6-(cyclopropylmethoxy)nicotinic acid synthesis

3synthesis methods
-

Yield:912454-38-7 87%

Reaction Conditions:

with potassium hydroxide in dimethyl sulfoxide at 100; for 0.133333 h;Inert atmosphere;Microwave irradiation;

References:

R?ver, Stephan;Andjelkovic, Mirjana;Bénardeau, Agnès;Chaput, Evelyne;Guba, Wolfgang;Hebeisen, Paul;Mohr, Susanne;Nettekoven, Matthias;Obst, Ulrike;Richter, Wolfgang F.;Ullmer, Christoph;Waldmeier, Pius;Wright, Matthew B. [Journal of Medicinal Chemistry,2013,vol. 56,# 24,p. 9874 - 9896]