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58130-38-4

5-AMINO-3,4-DIHYDROQUINOLIN-2(1H)-ONE synthesis

5synthesis methods
65887-63-0 Synthesis
5-Nitro-3,4-dihydroquinolin-2(1H)-one

65887-63-0
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Yield:58130-38-4 95%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in ethanol; for 4 h;

References:

Smid, Pieter;Coolen, Hein K. A. C.;Keizer, Hiskias G.;Van Hes, Rolf;De Moes, Jan-Peter;Den Hartog, Arnold P.;Stork, Bob;Plekkenpol, Rob H.;Niemann, Leonarda C.;Stroomer, Cees N. J.;Tulp, Martin Th. M.;Van Stuivenberg, Herman H.;McCreary, Andrew C.;Hesselink, Mayke B.;Herremans, Arnoud H. J.;Kruse, Chris G. [Journal of Medicinal Chemistry,2005,vol. 48,# 22,p. 6855 - 6869]

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