5-ACETYL-2-INDOLE CARBOXYLIC ACID synthesis
- Product Name:5-ACETYL-2-INDOLE CARBOXYLIC ACID
- CAS Number:31380-57-1
- Molecular formula:C11H9NO3
- Molecular Weight:203.19
31380-56-0
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77069-10-4
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31380-57-1
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105399-10-8
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Yield:31380-57-1 95% and 93%
Reaction Conditions:
with potassium hydroxide in ethanol;
Steps:
1 3-Acetyl-1H-indole-2-carboxylic acid (4b) and 5-Acetyl-1H-indole-2-carboxylic Acid (5b).
Saponification of 2b and 3b with 10% KOH in ethanol at 60° C. for 1 h followed by acidification with 1M HCl provided 3-acetyl-1H-indole-2-carboxylic acid 4b and 5-acetyl-1H-indole-2-carboxylic acid 5b in 95% and 93% yield respectively. The crude acids were used directly without purification in the next step.
References:
US2004/18986,2004,A1
127-17-3
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97776-06-2
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31380-57-1
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31380-56-0
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31380-57-1
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99-92-3
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31380-57-1
20 suppliers
$350.00/500mg