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ChemicalBook CAS DataBase List 5-(2-CHLORO-PHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID
334017-34-4

5-(2-CHLORO-PHENYL)-ISOXAZOLE-3-CARBOXYLIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: hydroxylamine hydrochloride; sodium methylate / ethanol / Reflux
2: potassium hydroxide / methanol / Reflux

References:

Vafadarnejad, Fahimeh;Saeedi, Mina;Mahdavi, Mohammad;Rafinejad, Ali;Karimpour-Razkenari, Elahe;Sameem, Bilqees;Khanavi, Mahnaz;Akbarzadeh, Tahmineh [Letters in drug design and discovery,2017,vol. 14,# 6,p. 712 - 717]

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