天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 4-Pentylcyclohexanone
61203-83-6

4-Pentylcyclohexanone synthesis

11synthesis methods
-

Yield: 74%

Reaction Conditions:

with 2,2,6,6-tetramethyl-piperidine;n-butyllithium in tetrahydrofuran;hexane at -20 - 20; for 16 h;Inert atmosphere;

Steps:

General procedure for the deprotection of 1,3-dioxolanes promoted by lithium 2,2,6,6-tetramethylpiperidide (Table 2 and Table 3)
General procedure: To a solution of 2,2,6,6-tetramethylpiperidine (TMP) (0.34 mL, 2.00 mmol, 4.0 equiv.) in THF (4 mL) was added n-BuLi (2.4 M in hexane, 0.83 mL, 2.00 mmol, 4.0 equiv.) at -20 or 0 . After stirring for 30 min, a solution of compound 1 or compound 4 (0.50 mmol, 1.0 equiv.) in THF (1 mL) was added. The resulting mixture was stirred before the completion of the reaction (monitored by TLC). Then the reaction mixture was poured into saturated NH4Cl solution (2.5 mL) at 0 and diluted with H2O (5 mL). The layers of the resulting mixture were separated and the aqueous layer was extracted with Et2O (4 × 15 mL). The combined organic layers were dried over Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by flash column chromatography on silica gel to afford products.

References:

Yuan, Changchun;Yang, Li;Yue, Guizhou;Yu, Tianzi;Zhong, Weiming;Liu, Bo [Tetrahedron Letters,2012,vol. 53,# 51,p. 6972 - 6976] Location in patent:supporting information

4-Pentylcyclohexanone Related Search: