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ChemicalBook CAS DataBase List 4-Nitrobenzenemethanesulfonic acid sodium salt
36639-50-6

4-Nitrobenzenemethanesulfonic acid sodium salt synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

with sodium sulfite in methanol;water;

Steps:

5.2

sodium (4-nitrophenyl)-methanesulfonate: A three-necked round bottom flask containing 285 mL of water was charged with sodium sulfite (76.6 g, 0.61 mol), methanol (190 mL) and 1-(chloromethyl)-4-nitrobenzene (94.8 g, 0.55 mol). The reaction mixture was heated to reflux overnight, cooled to ambient temperature. The precipitate was filtered, washed with ethanol and dried to give to give the title compound. LC-MS (m/z): 240 (M+1)+.

References:

US2008/103189,2008,A1 Location in patent:Page/Page column 38