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ChemicalBook CAS DataBase List 4-HYDROXY-6-METHOXYMETHYL-2-(METHYLTHIO)PYRIMIDINE
68087-13-8

4-HYDROXY-6-METHOXYMETHYL-2-(METHYLTHIO)PYRIMIDINE synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: N-chloro-succinimide / dichloromethane; N,N-dimethyl-formamide / 4 h / 20 °C
2: 2,6-dimethylpyridine / dichloromethane / 2 h / 0 - 20 °C
3: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1 h / 140 °C
4: boron tribromide / dichloromethane / 1 h / 0 °C

References:

WO2012/58187,2012,A1