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ChemicalBook CAS DataBase List 4-ETHYLPHENOXYACETIC ACID
24431-27-4

4-ETHYLPHENOXYACETIC ACID synthesis

4synthesis methods
-

Yield:24431-27-4 91%

Reaction Conditions:

Stage #1: ethyl 2-(4-ethylphenoxy)acetatewith sodium hydroxide in tetrahydrofuran; for 2 h;Reflux;
Stage #2: with hydrogenchloride in water; pH=1;

References:

Ozcan, Sevil;Kazi, Aslamuzzaman;Marsilio, Frank;Fang, Bin;Guida, Wayne C.;Koomen, John;Lawrence, Harshani R.;Sebti, Sa?d M. [Journal of Medicinal Chemistry,2013,vol. 56,# 10,p. 3783 - 3805] Location in patent:supporting information

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