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ChemicalBook CAS DataBase List 4-Chlorobiphenyl
2051-62-9

4-Chlorobiphenyl synthesis

15synthesis methods
-

Yield:2051-62-9 91.3%

Reaction Conditions:

with Ni(N,N'-bis(diphenylphosphino)-1,3-benzenediamine(-1H))Cl in tetrahydrofuran at 40; for 18 h;Schlenk technique;Inert atmosphere;Kumada Cross-Coupling;

Steps:

2.3. Typical procedure for the Kumada coupling reaction
General procedure: Aryl chloride (1.0 mmol), ArMgBr (1.5 mmol) in THF (2.0 mL), catalysts (2.0 mol%), were added to a Schlenk tube under an N2 atmosphere. The reaction was stirred at 40 °C for 12 h.

References:

Sun, Yunqiang;Li, Xiaoyan;Sun, Hongjian [Inorganica Chimica Acta,2014,vol. 415,p. 95 - 97]

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