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ChemicalBook CAS DataBase List 4-CHLORO-8-FLUORO-2-METHYLQUINOLINE
18615-59-3

4-CHLORO-8-FLUORO-2-METHYLQUINOLINE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: methanol / 7 h / 40 °C
2: diphenylether / 0.5 h / Reflux
3: trichlorophosphate / 3 h / Reflux

References:

Luo, Wei;Liu, Yang;Wang, Jian;Guo, Chun;Lu, Wei-Qiang;Cui, Kun-Qiang [Medicinal Chemistry Research,2012,vol. 21,# 10,p. 3073 - 3079,7]

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