4-Bromodiphenylamine synthesis
- Product Name:4-Bromodiphenylamine
- CAS Number:54446-36-5
- Molecular formula:C12H10BrN
- Molecular Weight:248.12
Yield:54446-36-5 90%
Reaction Conditions:
with potassium carbonate in methanol;water at 20; for 9 h;
Steps:
Typical Procedure: N-Arylation of Aniline with PhenylboronicAcid
General procedure: In a 50 mL round-bottomed flask, aniline (0.5 mmol), phenylboronicacid (1 mmol), K2CO3 (1.5 mmol), nanocatalyst (30 mol%with respect to aniline substrate) were added and stirred inMeOH-H2O (1:1) under air at r.t. for the required time, monitoringby TLC. After completion, the mixture was diluted with H2O,and the product was extracted with EtOAc (3×). The combined extracts were washed with brine (3×) and dried over Na2SO4.The product was purified by column chromatography (60-120mesh silica gel, eluting with EtOAc-hexane solvent).
References:
Borah, Raju Kumar;Raul, Prasanta Kumar;Mahanta, Abhijit;Shchukarev, Andrey;Mikkola, Jyri-Pekka;Thakur, Ashim Jyoti [Synlett,2017,vol. 28,# 10,p. 1177 - 1182]
122-39-4
341 suppliers
$14.00/5g
54446-36-5
201 suppliers
$12.00/1g
591-50-4
484 suppliers
$10.00/1g
106-40-1
468 suppliers
$12.00/5g
54446-36-5
201 suppliers
$12.00/1g
100-63-0
361 suppliers
$10.00/1g
106-40-1
468 suppliers
$12.00/5g
54446-36-5
201 suppliers
$12.00/1g
