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746651-80-9

4-BROMO-4'CARBOETHOXYBENZOPHENONE synthesis

2synthesis methods
-

Yield:746651-80-9 62%

Reaction Conditions:

Stage #1: (4-(ethoxycarbonyl)phenyl)zinc pivalatewith chloro-trimethyl-silane;copper(I) cyanide di(lithium chloride) in tetrahydrofuran at 0; for 0.5 h;Inert atmosphere;
Stage #2: 4-chlorobenzoyl chloride in tetrahydrofuran at 25; for 4 h;Inert atmosphere;

References:

Manolikakes, Sophia M.;Ellwart, Mario;Stathakis, Christos I.;Knochel, Paul [Chemistry - A European Journal,2014,vol. 20,# 38,p. 12289 - 12297] Location in patent:supporting information

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