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50545-45-4

4-(BENZYLOXY)-2-CHLORO-1-NITROBENZENE synthesis

3synthesis methods
-

Yield:-

Reaction Conditions:

with potassium carbonate in acetone;

Steps:

8 Preparation of benzyl 3-chloro-4-nitrophenyl ether STR22

EXAMPLE 8 Preparation of benzyl 3-chloro-4-nitrophenyl ether STR22 A mixture of 3-chloro-4-nitrophenol (10 g, 0.058 mole), benzyl bromide (11.8 g, 0.069 mole), and potassium carbonate (16 g, 0.116 mole) in acetone is stirred, heated at reflux temperature for 17 hours, cooled and filtered. The filtrate is concentrated in vacuo to give a solid residue which is recrystallized from absolute ethanol to give the title compound, mp 82°-84.5° C., identified by elemental and NMR analyses.

References:

US5324711,1994,A