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ChemicalBook CAS DataBase List 4-AMINODIBENZOFURAN
50548-43-1

4-AMINODIBENZOFURAN synthesis

6synthesis methods
50548-37-3 Synthesis
N-(Dibenzofuran-4-yl)acetamide

50548-37-3
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4-Dibenzofuranamine, 1,3-dibromo-

1332882-09-3
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Yield:50548-43-1 92%

Reaction Conditions:

with hydrogenchloride in methanol;4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Steps:

4 Synthesis of Compound 4

N-(dibenzo[b,d]furan-4-yl)acetamide (90 g, 400 mmol) was suspended in the mixture of concentrated HCl (240 mL) and methanol (240 mL). The reaction was refluxed for 2 h and then cooled to room temperature. Saturated sodium carbonate was used to neutralize the solution. The residue was collected by filtration and redissolved in DCM. After dried over sodium sulfate, the solution was concentrated to give dibenzo[b,d]furan-4-amine (67 g, 92% yield) as brown solid. Synthesis of 1,3-Dibromodibenzo[b,d]furan-4-amine.

References:

US2011/204333,2011,A1

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