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ChemicalBook CAS DataBase List 4,5-DIFLUOROPHTHALIC ANHYDRIDE
18959-30-3

4,5-DIFLUOROPHTHALIC ANHYDRIDE synthesis

3synthesis methods
-

Yield:18959-30-3 98%

Reaction Conditions:

with acetic anhydride at 120; for 12 h;

Steps:

2.1 5,6-Difluoro-1H-indene-1,3(2H)-one
Step 1: Add 100g of 4,5-difluorophthalic acid and 150ml of acetic anhydride to a three-necked reaction flask, then heat to 120°C to reflux, stop heating after 12 hours of reaction, and cool to room temperature to find white crystals precipitated. The above crystals were filtered and then washed with petroleum ether. The gray solid obtained after drying was 89 g (yield 98%)

References:

Nanjing Ounayi Organic Optoelectric Co., Ltd.;Xiao Shuyong;Yang Yali;Zhang Huili CN111470961, 2020, A Location in patent:Paragraph 0028-0030

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