4-(5-Chloropyridin-2-yl)morpholine synthesis
2synthesis methods
- Product Name:4-(5-Chloropyridin-2-yl)morpholine
- CAS Number:59027-83-7
- Molecular formula:C9H11ClN2O
- Molecular Weight:198.65
Yield:59027-83-7 78%
Reaction Conditions:
with dichloro[4,5-bis(diphenylphosphino)-9,9’-dimethylxanthene]palladium(II);sodium t-butanolate at 75;Inert atmosphere;Buchwald-Hartwig Coupling;
References:
Bourriquen, Florian;Bruneau-Voisine, Antoine;Jeandin, Aliénor;Stihle, Etienne;Fantasia, Serena [Chemistry - A European Journal,2019,vol. 25,# 38,p. 9006 - 9011] Location in patent:supporting information