ChemicalBook CAS DataBase List ((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER synthesis

11synthesis methods

Product Name:((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
CAS Number:376348-70-8
Molecular formula:C27H41N5O2
Molecular Weight:467.65

423165-08-6 Synthesis

3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane-p-toluenesulfonate

423165-08-6
32 suppliers
$188.00/250mg

(S)-tert-butyl 3-oxo-1-phenylpropylcarbamate

135865-78-0
96 suppliers
$64.00/100mg

((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

376348-70-8
8 suppliers
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Yield:376348-70-8 89%

Reaction Conditions:

with sodium tris(acetoxy)borohydride;acetic acid in 1,2-dichloro-ethane at 0 - 20; for 3 h;Inert atmosphere;

References:

Asano, Shigehiro;Gavrilyuk, Julia;Burton, Dennis R.;Barbas, Carlos F. [ACS Medicinal Chemistry Letters,2014,vol. 5,# 2,p. 133 - 137] Location in patent:supporting information

423165-07-5 Synthesis