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ChemicalBook CAS DataBase List (6R-trans)-3-(acetoxymethyl)-8-oxo-7-(1H-tetrazol-1-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
32510-61-5

(6R-trans)-3-(acetoxymethyl)-8-oxo-7-(1H-tetrazol-1-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 96 percent / D-aminoacid oxidase (DAO), glutaryl acylase (GA) / H2O / 2.5 h / pH = 8, O2
2: 98 percent / penicillin G acylase (PGA) / H2O / 4 °C / pH = 6.5

References:

Fernandez-Lafuente, Roberto;Guisan, Jose M.;Pregnolato, Massimo;Terreni, Marco [Tetrahedron Letters,1997,vol. 38,# 26,p. 4693 - 4696]

(6R-trans)-3-(acetoxymethyl)-8-oxo-7-(1H-tetrazol-1-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Related Search: