3-METHYL-THIOBENZAMIDE synthesis
- Product Name:3-METHYL-THIOBENZAMIDE
- CAS Number:2362-63-2
- Molecular formula:C8H9NS
- Molecular Weight:151.23
620-22-4
223 suppliers
$11.00/25mL
2362-63-2
81 suppliers
$11.00/1g
Yield: 87%
Reaction Conditions:
with sodiumsulfide nonahydrate in N,N-dimethyl-formamide at 130; for 2.5 h;
Steps:
The general procedure of preparing all thioamides
General procedure: Benzonitrile 1a (1 mmol), Na2S*9H2O (1.2 mmol) and DMF (1 mL) were added into a 10 mL bottle. The reactor was placed in a heating magnetic stirrer at 130 °C. After 2.5 h, by adding about 3 mL H2O after the reaction to disperse the solid product, the reaction mixture was extracted with EtOAc (3 x 3 mL), and the mixture was purified by column chromatography.
References:
Cao, Xian Ting;Yang, Huiyong;Zheng, Hui;Zhang, Pengfei [Heterocycles,2018,vol. 96,# 3,p. 509 - 517]
618-47-3
82 suppliers
$25.00/5g
2362-63-2
81 suppliers
$11.00/1g
1711-06-4
319 suppliers
$6.00/25g
2362-63-2
81 suppliers
$11.00/1g
99-04-7
450 suppliers
$8.00/100g
2362-63-2
81 suppliers
$11.00/1g